Why is your research important and how will it influence the understanding and treatment of MS?
Our research aims to enhance the efficacy of MS treatments. This is highly relevant for people under treatment who have to endure severe side effects. Mitoxantrone for example can only be given for a lifetime total of two years due to its negative effects on the heart. Being able to lower the effective dose will allow people to use this drug for longer. Further, while we are currently working with mitoxantrone as an example and proof of principle, I believe that our work will be able to enhance the delivery of other drugs as well. We are investigating the effects of our nanosized vehicles not only in context of drug efficacy but to further understand how interaction between these particles and the immune system can be exploited to improve patient outcome. Understanding these interactions will further allow us to fine tune these delivery methods.