WHY IS YOUR RESEARCH IMPORTANT AND HOW WILL IT INFLUENCE THE UNDERSTANDING AND TREATMENT OF MS?
Existing research on fatigue in MS has typically used research methods that involve large groups of patients and a focus on analysing the data at the group level. This tells us little about fatigue at the individual patient level. It is likely that fatigue fluctuations and triggers may differ substantially between people with MS, but group-based research focuses on results for the 'average' patient. The use of N-of-1 methods is novel in MS and it acknowledges that ‘every body is different’. Furthermore, if our interviews show that N-of-1 studies are feasible and acceptable to conduct with people with MS, we can extend our study protocol into other areas in MS. For example, we can use N-of-1 trials for testing treatments at the individual patient level, which provides personalised treatment results for each patient.