The role of diet in the development of multiple sclerosis in children

Dr Eleanor Dunlop

Deakin University, VIC

February 2023

specialisation: Social And Applied Research

focus area: Causes and Prevention

funding type: Fellowship

project type: Investigator Led Research

Summary

Although nutritional factors have long been of interest in multiple sclerosis (MS), little is known about the influence of diet on the likelihood of childhood-onset MS. 

Dietary intake information for children with MS and children without MS are available from a study conducted in Canada. Using this study, Dr Eleanor Dunlop will investigate whether diets, foods or nutrients may help to reduce the risk of MS onset in children. Dietary factors, including following an anti-inflammatory diet, consuming ultra-processed foods, dairy products, fish, unprocessed red meat and other nutrients, will be statistically tested in relation to childhood MS onset.   

The results will provide new insights into the role of diet in the risk of MS onset and potentially lead to evidence-based dietary guidance for children at high risk of developing MS.  

Progress

Dr Dunlop has completed testing the data for associations between childhood-onset MS and the consumption of dairy foods and ultra-processed foods. She is working on the completion of data analysis in relation to consumption of fish, consumption of unprocessed red meat, intake of macronutrients and intake of iron. 

A manuscript on associations between consumption of dairy foods and likelihood of paediatric MS has been prepared for publication. Similarly, a manuscript on associations between consumption of ultra-processed foods and likelihood of paediatric MS has been drafted.  

The publication of these results will help us understand the role of diet as a potential risk factor or protecting factor in the development of paediatric MS.  

Updated 31 March 2024

lead investigator

total funding

$150,000

start year

2023

duration

2 years

STATUS

Current project

Stages of the research process

Fundamental laboratory Research

Laboratory research that investigates scientific theories behind the possible causes, disease progression, ways to diagnose and better treat MS.

Lab to clinic timeline

10+ years

Translational Research

Research that builds on fundamental scientific research to develop new therapies, medical procedures or diagnostics and advances it closer to the clinic.

Lab to clinic timeline

5+ years

Clinical Studies and Clinical Trials

Clinical research is the culmination of fundamental and translational research turning those research discoveries into treatments and interventions for people with MS.

Lab to clinic timeline

3+ years

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The role of diet in the development of multiple sclerosis in children