Marginal structural models (MSM), a type of statistical model, are used to estimate causal links in observational/cohort data and therefore have been used to mimic clinical trials. However, there is an unmet need to broaden the current scope of what can be addressed by MSM, such as long-term effects of interventions, delayed effects of interventions and comparing multiple interventions.
The research team have developed this project to extend the present capabilities of MSM to include studies beyond the capabilities of clinical trials. These methods will enable researchers to use real-life data to draw conclusions about long-term and delayed treatment effects and compare multiple therapies.
Updated: 14 February, 2022
Laboratory research that investigates scientific theories behind the possible causes, disease progression, ways to diagnose and better treat MS.
Research that builds on fundamental scientific research to develop new therapies, medical procedures or diagnostics and advances it closer to the clinic.
Clinical research is the culmination of fundamental and translational research turning those research discoveries into treatments and interventions for people with MS.