Disability evolution and treatment impact in relapsing MS

Dr Valery Fuh-Ngwa

Menzies Institute for Medical Research, University of Tasmania, TAS

February 2025

specialisation: Neurobiology

focus area: Better treatments

funding type: Fellowship

project type: Investigator Led Research

Summary

One of the goals of managing MS is to control the progress of disabilities. More detailed predictions of disability status are needed to allow for more meaningful insights into MS disease progression.

Dr Valery Fuh-Ngwa aims to improve our understanding of relapsing MS and its treatment in adults. The project will use data from the Australian Multiple Sclerosis Longitudinal Study (AMSLS), the international MSBase registry and AusLong, to analyse the evolution of disability status and, in people experiencing severe active relapses, compare the effectiveness of standard MS treatments to stem cell treatments. Dr Fuh-Ngwa will show how new methods of analysing health outcomes can be used to monitor the health of individuals. Finally, the project will offer a hands-on practical course to teach students and MS researchers how to properly analyse health outcomes produced by MS studies.

In developing new ways to analyse health outcomes, Dr Fuh-Ngwa and his team will help us understand how disability progresses in people living with MS over time. The project will guide new approaches to treatment that may improve both the short and long-term health of people living with MS.

lead investigator

co-investigator

total funding

$225,000

start year

2025

duration

3 years

STATUS

Current project

Stages of the research process

Fundamental laboratory Research

Laboratory research that investigates scientific theories behind the possible causes, disease progression, ways to diagnose and better treat MS.

Lab to clinic timeline

10+ years

Translational Research

Research that builds on fundamental scientific research to develop new therapies, medical procedures or diagnostics and advances it closer to the clinic.

Lab to clinic timeline

5+ years

Clinical Studies and Clinical Trials

Clinical research is the culmination of fundamental and translational research turning those research discoveries into treatments and interventions for people with MS.

Lab to clinic timeline

3+ years

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Disability evolution and treatment impact in relapsing MS