Stopping T cells entering the brain in MS

Dr Iain Comerford

University of Adelaide

| Better treatments | Immunology | Fellowship | 2022 | Investigator Led Research |


In MS, cells of the immune system enter the brain and spinal cord and produce substances that cause inflammation, resulting in damage that leads to the disease symptoms. Understanding how the immune cells enter the brain is likely to lead to better therapeutics that can interfere with this process.  

This project will focus on the ways in which inflammatory immune cells called T cells, enter the brain. New ways to block inflammatory T cell migration will be tested and the disease-causing T cells will be examined in more detail in this study. 

This project should identify new ways in which MS may be better treated in the future. 

Updated: 14 February, 2022

Stages of the research process

Fundamental laboratory

Laboratory research that investigates scientific theories behind the possible causes, disease progression, ways to diagnose and better treat MS.

Lab to clinic timeline: 10+ years

Research that builds on fundamental scientific research to develop new therapies, medical procedures or diagnostics and advances it closer to the clinic.

Lab to clinic timeline: 5+ years
Clinical Studies
and Clinical Trials

Clinical research is the culmination of fundamental and translational research turning those research discoveries into treatments and interventions for people with MS.

Lab to clinic timeline: 1-5 years


Grant Awarded

  • Fellowship Grant

Total Funding

  • $390,000


  • 3 years

Funding Partner

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Stopping T cells entering the brain in MS