Tell us about your current research project...
In the immune system, regulatory T cells (Tregs) are responsible for controlling the inflammation driven by effector T cells. However, in MS, Tregs are unable to control these effector T cells leading to attacks on the central nervous system. This project will investigate whether Tregs in people with Clinically Isolated Syndrome (CIS), the first clinical sign of MS, are abnormal. This will help identify how early this immune imbalance occurs and yield insight into disease initiation.