News

How to distinguish nicotine withdrawal from MS relapses

29 May 2026

You may experience nicotine withdrawal symptoms when you attempt to quit smoking. This affects around 50% of all smokers and occurs regardless of how much you have smoked in the past.

Some withdrawal symptoms can be similar to symptoms that occur during an MS relapse. If you don’t feel well while quitting smoking, it can be helpful to distinguish whether your symptoms are more likely to be a sign of an MS relapse or due to nicotine withdrawal.

On the one hand, there are symptoms that can occur during nicotine withdrawal that are atypical for MS. These include insomnia, restlessness, irritability and anger, increased appetite, and weight gain. Nicotine withdrawal symptoms are strongest in the first few days and usually subside almost completely within 3-4 weeks.

On the other hand, there are symptoms that are typical of an MS relapse and not typical of nicotine withdrawal. These include vision problems, sensory disturbances of the skin, paralysis, coordination disorders, speech problems, pain and incontinence.

Finally, there are symptoms that can occur with both nicotine withdrawal and an MS relapse. These include difficulties with concentration and attention, depression and mood, a general feeling of being unwell and exhaustion.

Being aware of these differences can help make quitting smoking as stress-free as possible. However, if you experience symptoms that you are unsure about, don’t hesitate to seek help.

Need support to quit smoking?
Quit offers free information, tools and support services to help people quit smoking.

Video credits:
Project team: Alex Keller, Daniel Kotz, Martin Winter, Chris Friemel, Christoph Heesen, Karin Riemann-Lorenz, Claudia Marck
Digital creator: Alexander Wohler

Related News

MS News

The MS-smoke cocktail

29 May 2026

MS and smoking cigarettes both damage the central nervous system, which includes the brain and spinal cord. This damage can be noticed in many different ways, such as sensory disturbances or vision problems.

MS News

How smoking can affect the effectiveness of MS medications

29 May 2026

Studies have shown that smoking can reduce the effectiveness of MS medications. While the exact mechanisms are not yet fully understood, it is considered likely that inhalation of cigarette smoke plays an important role and promotes the formation of antibodies.  

Read More

Newsletter subscription

  • This field is for validation purposes and should be left unchanged.

How to distinguish nicotine withdrawal from MS relapses