Investigating the role of neutrophils in MS

Dr Stephanie Trend

Telethon Kids Institute and Perron Institute

| Causes and Prevention | Immunology | Incubator | 2022 | Investigator Led Research |


MS is caused by the immune system mistakenly attacking the body. What causes this mistake in unclear, but what is known is that it probably involves both B and T cells, two types of immune cells. However, the role of neutrophils (a type of white blood cell) is unknown.

The research team has recently shown that B cells might be activated by proteins produced by neutrophils. The team will now investigate whether there is any link between the two cell types in people with early MS. If neutrophils are found to be important in triggering B cells in MS, then new drugs might be developed to target them in the future. 

Updated: 14 February, 2022

Stages of the research process

Fundamental laboratory

Laboratory research that investigates scientific theories behind the possible causes, disease progression, ways to diagnose and better treat MS.

Lab to clinic timeline: 10+ years

Research that builds on fundamental scientific research to develop new therapies, medical procedures or diagnostics and advances it closer to the clinic.

Lab to clinic timeline: 5+ years
Clinical Studies
and Clinical Trials

Clinical research is the culmination of fundamental and translational research turning those research discoveries into treatments and interventions for people with MS.

Lab to clinic timeline: 1-5 years


Grant Awarded

  • Incubator Grant

Total Funding

  • $24,073


  • 1 year

Funding Partner

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Associate Professor Yasmine Probst

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Investigating the role of neutrophils in MS